Table 1.
German patients n = 176 | Brazilian patients n = 91 | p | |
---|---|---|---|
Age, years | 62.43 ± 12.33 | 56.3 ± 12.62 | < 0.001 |
Age > 65 years | 87 (49.4%) | 24 (26.3%) | < 0.001 |
Women | 138 (78.4%) | 84 (92.3%) | < 0.001 |
Smoking | 16 (12.9%) | No information | |
Marital status | |||
Married | 114 (64.8%) | 32 (35.2%) | 0.001 |
Single | 19 (10.8%) | 32 (35.2%) | 0.001 |
Divorced | 9 (5.1%) | 13 (14.3%) | 0.001 |
Widow | 26 (14.8%) | 13 (14.3%) | 0.001 |
Having children | 140 (79.5%) | 66 (74.2%) | 0.013 |
Laboral situation | |||
Employed | 56 (31.8%) | 32 (35.2%) | 1.00 |
Retired | 116 (65.9%) | 59 (64.8%) | 0.283 |
Incapacitated | 4 (2.2%) | 0 | |
RA duration, years | 14.35 ± 10.41 | 15.9 6 ± 10.28 | 0.234 |
Positive rheumatoid factor | 104/148 (70.3%) | 18/31 (60.0%) | 0.042 |
Positive ACPA | 91/125 (72.8%) | 5/29 (17.2%) | 0.000 |
Erosive disease | 70 (51.1%) | 40 (43.9%) | 0.011 |
DAS28-CRP | 3.30 ± 1.35 | 3.42 ± 1.51 | 0.307 |
CRP, mg/L | 5.82 ± 10.45 | 7.78 ± 18.3 | 0.028 |
HAQ-DI | 1.01 ± 0.75 | 1.89 ± 1.85 | 0.012 |
HAQ-DI > 0.5 | 65.5% | 64.1% | 0.908 |
Treatment | |||
Glucocorticoid (Gc), low dose | 10 (5.7%) | 2 (3.4%) | < 0.001 |
csDMARD ± Gc | 68 (48.2%) | 44 (74.6%) | 0.003 |
bDMARD + csDMARD + Gc | 33 (23.4%) | 5 (8.5%) | 1.00 |
bDMARD + csDMARD | 5 (3.5%) | 4 (6.8%) | 1.00 |
bDMARD ± Gc | 19 (13.5%) | 3 (5.6%) | 1.00 |
bDMARD biological disease modifying anti-rheumatic drug; CRP C-reactive protein; csDMARD conventional synthetic DMARD; DAS disease activity score; HAQ-DI Health Assessment Questionnaire Disability Index; SEM standard error of the mean