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. 2021 May 1;397(10285):1625–1636. doi: 10.1016/S0140-6736(21)00590-0

Figure 2.

Figure 2

Association between the intensity of blood pressure reduction and relative treatment effects for prevention of major cardiovascular events

The centre of the bubbles indicates the HR for each trial, with the size of the bubble inversely proportional to the respective SE. The solid red line is the fitted regression line; the dashed blue lines indicate 95% CI; and the dashed grey line indicates HR=1·0. HR=hazard ratio. *Excluding the first 12 months after randomisation.