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. 2021 May 7;6:174. doi: 10.1038/s41392-021-00550-2

Table 1.

Baseline characteristics of 12 severely immunosuppressed AIDS patients enrolled in AAIT

Patient Gender Age (years) Transmission
route
Laboratory examinations Viral nucleic acid ART relative to initiation of AAIT (days) Times of
transfusion
Dose of each transfusion
108/kg
HIV RNA
(copies/ml)
CD4
(cells/μl)
CD8
(cells/μl)
WBC
(109/L)
RBC (1012/L) PLT
(109/L)
HGB
(g/L)
ALT
(U/L)
AST
(U/L)
Cre
(μmol/L)
CMV
(IU/ml)
EBV
(IU/ml)
HBV
(copies/ml)
HCV
(copies/ml)
01-W M 36 Heterosexual <20 33 602 5.43 3.37 352 105 9 18 81 <100 2.58E+02 <40 <50 −104 5

3/2.5/2.5/

2.5/2.5

02-Z M 28 Heterosexual 2.17E+04 7 227 1.31 2.59 136 78 20 42 53 <100 1.97E+02 <40 <50 −28 4 3/3.1/3/3
03-G M 18 Homosexual 2.32E+06 9 688 3.15 4.18 131 121 58 35 74 <100 <100 <40 <50 −5 3 3/3.5/2.6
04-D M 35 Homosexual 1.62E+02 1 40 1.75 3.05 170 87 18 24 63 4.17E+02 <100 <40 <50 −58 3 2.6/2.9/2.9
05-Z M 29 Homosexual 8.88E+05 32 778 1.88 4.41 142 127 95 68 88 <100 <100 <40 <50 +20 3 3/2.6/2.6
06-L M 44 Homosexual 1.01E+06 11 90 6.25 4.38 394 128 40 38 62 1.74E+04 6.64E+02 <40 <50 −10 2 3/2.5
07-X M 34 Unknown 1.76E+07 4 590 3.16 4.44 239 127 29 46 84 <100 <100 <40 <50 −6 3 3.5/3/3
08-D M 54 Homosexual 2.20E+05 10 268 7.09 4.66 325 151 33 18 85 <100 <100 <40 <50 +8 2 3/3
09-L F 31 Heterosexual 1.25E+07 13 474 4.27 3.96 87 127 94 98 47 1.27E+03 <100 <40 <50 +2 3 3.3/3.2/3.2
10-L M 35 Heterosexual 4.47E+05 20 374 4.32 3.76 278 121 47 27 74 <100 <100 <40 <50 +7 2 3.5/2.6
11-S M 39 Unknown 2.53E+05 7 258 2.29 5.83 281 165 59 39 69 <100 <100 <40 <50 −3 2 3.1/3
12-L M 27 Homosexual 8.86E+04 15 459 2.87 4.63 106 133 112 32 72 3.04E+04 <100 <40 <50 +2 2 3.3/3

“−” means ART before AAIT treatment, “+” means ART after AAIT treatment

M male, F female, WBC white blood cell, RBC red blood cell, PLT platelet, HGB hemoglobin, ALT alanine aminotransferase, AST glutamic oxaloacetic transaminase, Cre creatinine, CMV cytomegalovirus, EBV Epstein–Barr virus, HBV hepatitis B virus, HCV hepatitis C virus