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. 2021 Apr 8;53(4):615–630. doi: 10.1038/s12276-021-00586-y

Fig. 1. Novel AluYa5 insertion events in the 3’UTRs of the SIRPB1 and XPR1 genes.

Fig. 1

Polymorphic insertion testing was performed for two AluYa5 insertions located in the 3’UTR regions of the a SIRPB1 and b XPR1 genes. A screenshot of the UCSC human genome browser (hg19) shows the location of each AluYa5 insertion in the 3’UTR of each gene; adjacent repeats are displayed in gray boxes. The results of PCR amplification from a panel of 80 geographically diverse individuals and 38 Korean samples are shown in this figure (Supplementary Table S4). The upper and lower bands denote the presence of an AluYa5 insertion and its absence, respectively. c The blue box shows the identical sequences of miRNA (hsa-miR-619) binding to the AluYa5 elements inserted in the 3’UTR regions of the SIRPB1 and XPR1 genes.