Table 1.
Aβ(−) SVCI |
Aβ(−) NC (n = 198) | ||||
---|---|---|---|---|---|
Total (n = 198) | svMCI (n = 116) | SVaD (n = 82) | p-value | ||
Demographics | |||||
Age, years | 75.2 ± 7.2* | 74.4 ± 7.6 | 76.3 ± 6.4* | 73.3 ± 6.7 | 0.004 |
Gender, female | 135 (68.2%) | 79 (68.1%) | 56 (68.3%) | 127 (64.1%) | 0.697 |
Education, years | 8.8 ± 5.2* | 9.0 ± 5.1* | 8.5 ± 5.4* | 10.5 ± 4.8 | 0.002 |
MMSE | 23.3 ± 4.5* | 25.8 ± 2.7* | 19.7 ± 4.2* | 27.9 ± 2.0 | < 0.001 |
Neuropsychological test | |||||
Attention | |||||
Digit Span Test Backward | 2.9 ± 1.1* | 3.2 ± 0.9* | 2.5 ± 1.2* | 3.7 ± 1.1 | < 0.001# |
Language | |||||
K-BNT | 36.1 ± 10.4* | 39.7 ± 9.6* | 31.1 ± 9.4* | 47.1 ± 6.8 | < 0.001# |
Visuospatial function | |||||
RCFT: copying | 23.8 ± 9.6* | 27.8 ± 6.5* | 18.1 ± 10.3* | 32.0 ± 4.0 | < 0.001# |
Memory | |||||
SVLT: delayed recall | 2.9 ± 2.8* | 4.1 ± 2.7* | 1.2 ± 1.8* | 6.6 ± 2.1 | < 0.001# |
RCFT: delayed recall | 7.2 ± 6.4* | 10.0 ± 6.2* | 3.3 ± 4.1* | 13.6 ± 6.3 | < 0.001# |
Frontal/executive function | |||||
COWAT: animal | 9.7 ± 4.1* | 11.5 ± 3.7* | 7.2 ± 3.2* | 15.3 ± 4.5 | < 0.001# |
COWAT: phonemic | 14.1 ± 9.6* | 17.1 ± 9.4* | 9.1 ± 7.6* | 25.1 ± 10.7 | < 0.001# |
Stroop test: color reading | 48.6 ± 28.4* | 58.9 ± 25.0* | 31.0 ± 25.2* | 82.4 ± 20.3 | < 0.001# |
Values are presented as mean ± standard deviation. The p values were obtained by analysis of variance model and chi-square tests.
The p values were obtained by analysis of covariance after controlling for age and education.
p < 0.05 compared to Aβ(−) NC.