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. 2021 May 6;11:9649. doi: 10.1038/s41598-021-89084-9

Table 1.

Counts of miRNAs identified DESEq2 and limma.

Epilepsy onset Epilepsy stage Raw reads > 500 Normalised reads > 500 p-value < 0.05
FC > 1.4
reads > 500
p-value < 0.01
FC > 1.4
reads > 500
DESeq2 limma DESeq2 limma DESeq2 limma DESeq2 limma
Adulthood Acute 334 348 313 335 36 40 29 40
Latent 370 380 359 371 42 36 37 36
Chronic 394 400 380 385 38 30 21 30
Infancy Acute 331 339 324 311 27 25 21 25
Latent 365 380 368 378 3 3 1 3
Chronic 407 419 376 395 12 15 4 15

Descriptive results of two workflows of massive parallel sequencing data processing: DESeq2 and limma. The table contains count of miRNAs reaching threshold of 500 reads (both raw and normalised) in each statistical analysis. Counts of miRNAs with fold-change over 1.4, p-value below 0.05 or 0.01 and number of normalised reads above 500 are displayed for each stage of epileptogenesis in both age groups respectively.