Table 2a.
Patient characteristics and right heart catheterisation data for the validation cohort
| Validation cohort - MHH | All | Pre-capillary PH* | Post-capillary PH† | Combined pre- and post-capillary PH‡ | PH ruled out |
|---|---|---|---|---|---|
| Patient characteristics | |||||
| n (%) | 703 (100) | 459 (65) | 42 (6) | 111 (16) | 91 (13) |
| Age, years | 66 ± 14 | 64 ± 15 | 73 ± 8 | 71 ± 12 | 63 ± 13 |
| Female/male, n/n | 407/296 | 253/206 | 24/18 | 70/41 | 60/31 |
| BMI, kg•m−2 | 26.9 [23.9; 31.2] | 26.5 [23.3; 30.5] | 29.2 [25.7; 32.6] | 29.1 [25.7; 34.7] | 25.4 [23.0; 29.7] |
| Right heart catheterisation data | |||||
| mPAP, mmHg | 36 [26; 47] | 39 [30; 48] | 29 [26; 32] | 43 [37; 50] | 17 [14; 19] |
| PVR, WU | 6 ± 5 | 8 ± 5 | 2 ± 1 | 6 ± 3 | 2 ± 1 |
| Cardiac index, L•min−1•m−2 | 2.4 ± 0.7 | 2.3 ± 0.7 | 2.7 ± 0.8 | 2.3 ± 0.6 | 2.8 ± 1.0 |
| PAWP, mmHg | 11.4 ± 5.5 | 9.4 ± 3.4 | 19.4 ± 3.0 | 19.5 ± 3.3 | 7.3 ± 2.9 |
| RAP, mmHg | 8.0 ± 4.9 | 7.6 ± 4.5 | 10.6 ± 5.3 | 11.9 ± 4.8 | 3.6 ± 2.4 |
| Echocardiographic data | |||||
| TRG, mmHg (n = 699) | 51 ± 20 | 54 ± 19 | 42 ± 13 | 57 ± 17 | 29 ± 9 |
| PASP, mmHg (n = 698) | 60 ± 21 | 63 ± 20 | 51 ± 14 | 68 ± 17 | 35 ± 10 |
| RVOT AT, ms (n = 595) | 95 ± 43 | 88 ± 42 | 122 ± 55 | 93 ± 32 | 121 ± 44 |
| IVC diameter, mm (n = 697) | 20 ± 6 | 20 ± 6 | 21 ± 5 | 22 ± 6 | 16 ± 5 |
| RA area, cm2 (n = 446) | 27 ± 17 | 28 ± 20 | 21 ± 5 | 29 ± 10 | 19 ± 6 |
| TAPSE/TRG, mm•mmHg−1 (n = 693) | 0.47 ± 0.34 | 0.40 ± 0.25 | 0.54 ± 0.18 | 0.39 ± 0.46 | 0.88 ± 0.36 |
| TRG/RVOT AT, mmHg•ms−1 (n = 594) | 0.81 ± 1.58 | 0.90 ± 1.49 | 1.04 ± 3.72 | 0.69 ± 0.33 | 0.39 ± 1.21 |