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. 2021 Apr 23;12:664364. doi: 10.3389/fimmu.2021.664364

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Copyright © 2021 Zhou, Jiang, Cai, Zeng and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Magnetic Resonance Imaging Findings. (A–C) At first onset, MRI demonstrated patchy lesions in the medulla oblongata and dorsal pons; (D–F) At first recurrence, MRI demonstrated multiple lesions in the brain; (G, H) At second onset, MRI demonstrated pons lesions, consistent with the diagnosis of multiple sclerosis; (I–K) Before teriflunomide administration, MRI demonstrated new punctate enhancing lesions in the left frontal lobe and abnormal signals in the thoracic spinal cord at T6-7 of the skull and spinal cord; (L–N) After 6 months of teriflunomide use, MRI demonstrated that the lesions were reduced, especially in the spinal cord; (O, P) After 1 year of teriflunomide use, MRI demonstrated that the patient’s lesions were reduced. The arrowhead showing lesions in MRI. MRI, Magnetic resonance imaging.