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. 2021 Apr 23;12:592731. doi: 10.3389/fimmu.2021.592731

Table 2.

Pre and post pentavalent vaccination antibody titres against tetanus, diphtheria toxoid, Haemophilus influenza B and Bordetella pertussis.

Name of antibody Baseline Post pentavalent vaccination
  PT1 (n=33) PT2 (n=80) FT (n=80) PT1 (n=24) PT2 (n=55) FT (n=54)
Anti-Tetanus- IgG            
% Seroprotection and 95% CI (≥0.01 IU/ml) 100 (100–100) 100 (100–100) 100 (100–100) 100 (100–100) 100 (100–100) 100 (100–100)
% Seroprotection and
95% CI (≥0.1 IU/ml)
93.93 (89.91–100) 100 (100–100) 100 (100–100) 100 (100–100) 100 (100–100) 100 (100–100)
GMT 1.56 2.71 3.57 1.44 1.47 1.82
Anti-Diphtheria-IgG
% Seroprotection and
95% CI (≥0.01 IU/ml)
87.87 (76–99.75) 92.5 (86.23–98.76) 97.5 (94.07–100.92) 100 (100–100) 100 (100–100) 100 (100–100)
% Seroprotection and
95% CI (≥0.1 IU/ml)
0 18.75 (9.47–28.02) 25 (15.51–34.48) 91.66 (81.6–100) 98.18 (95–100) 98.14 (95.19–100)
GMT 0.02 0.04 0.05 0.53 0.65 0.70
Anti PRP-IgG
% Seroprotection and 95% CI (≥0.15 µg/ml) 81.81 (67.78–95.85) 70 (59.1–80.89) 72.5 (62.71–82.28) 95.83 (88.56–100) 100 (100–100) 98.14 (95.19–100)
% Seroprotection and 95% CI (≥1 µg/ml) 6.06 (0–14.74) 12.5 (4.63–20.36) 16.25 (8.16–24.33) 54.16 (36.03–72.3) 80 (70.49–89.5) 90.74 (84.38–97.09)
GMT 0.21 0.32 0.35 1.58 4.20 7.71
Anti-Pertussis-IgG
% Seroprotection and 95% CI (>20 U/ml) 0 (0–0) 6.25 (0.49–12) 5 (0.22–9.77) 75 (59.23–90.76) 72.72 (62.14–83.31) 74.07 (64.47–83.67)
GMT 0.050 0.67 0.16 29.23 25.64 30.28

GMT, geometric mean titer; 95% CI, 95% confidence interval.