Table 2.
Pre and post pentavalent vaccination antibody titres against tetanus, diphtheria toxoid, Haemophilus influenza B and Bordetella pertussis.
| Name of antibody | Baseline | Post pentavalent vaccination | ||||
|---|---|---|---|---|---|---|
| PT1 (n=33) | PT2 (n=80) | FT (n=80) | PT1 (n=24) | PT2 (n=55) | FT (n=54) | |
| Anti-Tetanus- IgG | ||||||
| % Seroprotection and 95% CI (≥0.01 IU/ml) | 100 (100–100) | 100 (100–100) | 100 (100–100) | 100 (100–100) | 100 (100–100) | 100 (100–100) |
| % Seroprotection and 95% CI (≥0.1 IU/ml) |
93.93 (89.91–100) | 100 (100–100) | 100 (100–100) | 100 (100–100) | 100 (100–100) | 100 (100–100) |
| GMT | 1.56 | 2.71 | 3.57 | 1.44 | 1.47 | 1.82 |
| Anti-Diphtheria-IgG | ||||||
| % Seroprotection and 95% CI (≥0.01 IU/ml) |
87.87 (76–99.75) | 92.5 (86.23–98.76) | 97.5 (94.07–100.92) | 100 (100–100) | 100 (100–100) | 100 (100–100) |
| % Seroprotection and 95% CI (≥0.1 IU/ml) |
0 | 18.75 (9.47–28.02) | 25 (15.51–34.48) | 91.66 (81.6–100) | 98.18 (95–100) | 98.14 (95.19–100) |
| GMT | 0.02 | 0.04 | 0.05 | 0.53 | 0.65 | 0.70 |
| Anti PRP-IgG | ||||||
| % Seroprotection and 95% CI (≥0.15 µg/ml) | 81.81 (67.78–95.85) | 70 (59.1–80.89) | 72.5 (62.71–82.28) | 95.83 (88.56–100) | 100 (100–100) | 98.14 (95.19–100) |
| % Seroprotection and 95% CI (≥1 µg/ml) | 6.06 (0–14.74) | 12.5 (4.63–20.36) | 16.25 (8.16–24.33) | 54.16 (36.03–72.3) | 80 (70.49–89.5) | 90.74 (84.38–97.09) |
| GMT | 0.21 | 0.32 | 0.35 | 1.58 | 4.20 | 7.71 |
| Anti-Pertussis-IgG | ||||||
| % Seroprotection and 95% CI (>20 U/ml) | 0 (0–0) | 6.25 (0.49–12) | 5 (0.22–9.77) | 75 (59.23–90.76) | 72.72 (62.14–83.31) | 74.07 (64.47–83.67) |
| GMT | 0.050 | 0.67 | 0.16 | 29.23 | 25.64 | 30.28 |
GMT, geometric mean titer; 95% CI, 95% confidence interval.