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. 2021 Apr 23;11:639108. doi: 10.3389/fcimb.2021.639108

Table 1.

Available diagnostic methods for COVID-19.

Test Detection type Positive rate Time Characteristics Limitations References
qRT-PCR nucleic acid detection 38% >2h Currently the most common detection method, simple quantitative detection. Time-consuming, poor sensitivity (Liu R. et al., 2020)
ELISA Immunological detection 80.4% >2h Fast, easy to operate, low sample volumes Cross-reactivity, Antibodies are produced about 7-10 days after infection. (Liu W. et al., 2020)
RT-LAMP nucleic acid detection 92.9% 40–60 min Highly sensitive, fast, and convenient field testing Prone to false positives (Baek et al., 2020)
CRISPR-based detection nucleic acid detection 96% 30-60min Highly sensitive, high specificity, fast and convenient for field testing., low-cost Not yet widespread and in clinical trials (Patchsung et al., 2020)
ddPCR nucleic acid detection 40% NA Absolute quantification, high sensitivity Expensive equipment, poor accessibility, and complexity of the operation (Suo et al., 2020)
CT Scan Radiological Screening NA NA Check for disease progression, easy access, rapid detection Unable to identify the pathogen of infection, clinical assistant tests (Dong et al., 2020)