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. 2021 Apr 23;12:643771. doi: 10.3389/fimmu.2021.643771

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Copyright © 2021 Mehta, Kadel, Townsend, Oliwa and Guerriero.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Macrophage-targeting strategies for anti-cancer therapy have started to fill our toolbox. We now need to understand how these compounds work, which subsets of TAMs they modulate, and which breast cancer patients will benefit.