Table 4.

The quantified histopathological changes of rat livers in hematoxylin and eosin stained sections. Results are expressed as mean ± SEM; n = 3.

Groups	Nuclear pyknosis	Fat deposit
Control	0.08 ± 0.02	0.12 ± 0.01
Diabetic	1.64 ± 0.21###	2.06 ± 0.15###
Diabetic + glibenclamide	1.10 ± 0.07###,*	1.40 ± 0.09###,***
Diabetic + EBRE (100 mg/kg)	1.20 ± 0.14###	1.82 ± 0.11###
Diabetic + EBRE (200 mg/kg)	1.14 ± 0.10###	1.64 ± 0.08###,*
Diabetic + EBRE (400 mg/kg)	1.02 ± 0.07###,**	1.50 ± 0.06###,**

EBRE, Eryngium billardieri root extract. *P < 0.05, **P < 0.01, and ***P < 0.001 indicate significant differences compared to the diabetic group; ^###P < 0.001 versus control group.