Table 6.
Human skin irritation test for 11 volunteers and the grading scale.
| Materials | Time (h) | ||||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 24 | 48 | 72 | |
| Number of volunteers (grading scale)* | |||||||
| T. indica coating | 11 (0) | 11 (0) | 11 (0) | 11 (0) | 11 (0) | 11 (0) | 11 (0) |
| C. fistula coating | 11 (0) | 11 (0) | 11 (0) | 11 (0) | 11 (0) | 11 (0) | 11 (0) |
| Positive control (15% (w/v) SLS) | 10 (0) | 9 (0) | 10 (0) | 10 (0) | 11 (0) | 11 (0) | 11 (0) |
| 1 (1+) | 2 (1+) | 1 (1+) | 1 (1+) | ||||
| Negative control (distilled water) | 11 (0) | 11 (0) | 11 (0) | 11 (0) | 11 (0) | 11 (0) | 11 (0) |
*0, No reaction; 1+, weakly positive reaction (usually characterized by mild erythema and/or dryness across most of the treatment site); 2+, moderately positive reaction (usually distinct erythema and/or dryness, possibly spreading beyond of the treatment site); 3+, strongly positive reaction (strong and often spreading erythema with edema and/or eschar formation). SLS, Sodium lauryl sulfate.