Table 1.
Outcome of neonates borne to COVID-19–positive mothers (n=44)
| Parameter | Delivered at our instituteb) (mothers=28, neonates=30) | Delivered at non-COVID facility after dischargea) (mothers=13, neonates=14) | Overallc) (mothers=41, neonates=44) | |
|---|---|---|---|---|
| Delivery details | (n=28) | (n=13) | (n=41) | |
| Mode of delivery | ||||
| Vaginal delivery | 13 (46.4)a) | 5 (38.4) | 18 (44)a) | |
| Cesarean delivery | 15 (53.5)a) | 8 (61.5)a) | 23 (56)b) | |
| Indication of cesarean delivery | ||||
| Fetal distress | 6 (21.4) | 2 (15.3) | 8 (19.6) | |
| Previous cesarean delivery | 5 (17.8) | 3 (23) | 8 (19.6) | |
| Breech presentation | 1 (3.5) | 2 (15.3) | 3 (7.3) | |
| Cephalopelvic disproportion | 1 (3.5) | 0 (0) | 1 (2.4) | |
| Nonprogress of labor | 0 (0) | 1 (7.6) | 1 (2.4) | |
| Term PROM with failed induction | 2 (7.1) | 0 (0) | 2 (4.8) | |
| Viral detection-delivery interval (day) | 2.89±1.62 | 18.92±6.46 | 7.97±8.45 | |
| <7 | 28 (100) | 0 (0) | 28 (68.3) | |
| 8–14 | 0 (0) | 4 (30.7) | 4 (9.7) | |
| >14 | 0 (0) | 9 (69.2) | 9 (21.95) | |
| Single or multiple gestations | ||||
| Singleton | 26 (92.8) | 12 (92.3) | 38 (92.6) | |
| Twin | 2 (7.1) | 1 (7.6) | 3 (7.3) | |
| Gestational age at the time of delivery (wk) | ||||
| 28–32 | 1 (3.6) | 0 (0) | 1 (2.4) | |
| 32–34 | 2a) (7.1) | 0 (0) | 2 (4.9) | |
| 34–36.6 | 3 (10.7) | 0 (0) | 3 (7.3) | |
| >37 | 22a) (78.6) | 13a) (100) | 35 (85.4) | |
| Vertical transmission | ||||
| Positive neonatal Nasopharyngeal RT-PCR for COVID-19 (n=30) | 2 (6.6) | Not done | ||
| Biological Samples for COVID-19 RT-PCR (n=22) | Not done | |||
| Cord blood | Negative in all (100) | |||
| Placental membrane swab | Negative in all (100) | |||
| Vaginal fluid | Negative in all (100) | |||
| Amniotic fluid | Negative in all (100) | |||
| Peritoneal fluid (n=10 CS) | Negative in all (100) | |||
| Breast milk for COVID-19 RT-PCR (n=23) | Negative in 23 (100) | Not done | ||
| Neonatal details | (n=30) | (n=14) | (n=44) | |
| Maturity | ||||
| Term | 23 (76.6) | 14 (100) | 37 (84.1) | |
| Preterm | 7 (23.3) | 0 (0) | 7 (15.9) | |
| Birth weight (kg) | 2.51±0.64 | 2.79±0.33 | 2.60±0.57 | |
| >2.5 | 19 (63.3) | 12 (85.7) | 31 (70.4) | |
| 1.5–2.5 | 9 (30) | 2(14.2) | 11 (25) | |
| <1.5 | 2 (6.6) | 0 (0) | 2 (4.5) | |
| Sex | ||||
| Male | 16 (53.3) | 8 (57.1) | 24 (54.5) | |
| Female | 14 (46.6) | 6 (42.8) | 20 (45.5) | |
| Apgar score | ||||
| <7 at 5 min | 5 (16.6) | 0 (0) | 5 (11.4) | |
| >7 at 5 min | 25 (83.3) | 14 (100) | 39 (88.6) | |
| Birth asphyxia | 5 (16.6) | 0 (0) | 5 (11.4) | |
| NICU admission | 6 (20) | 0 (0) | 6 (13.6) | |
| Neonatal death | 0 (0) | 0 (0) | 0 (0) | |
| Roomed in & breast fed | 9 (30) | 14 (100) | 23 (52.2) | |
Values are presented as number (%) or mean±standard deviation.
COVID-19, coronavirus disease 2019; PROM, premature rupture of membranes; RT-PCR, reverse transcription-polymerase chain reaction; CS, cesarean section; NICU, neonatal intensive care unit.
a)
One twin delivery.
b)
Two twin deliveries.
c)
Three twin deliveries.