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. 2021 Mar 16;13(5):e13466. doi: 10.15252/emmm.202013466

Figure EV1. Tumor‐promoting genes are not frequently altered in cutaneous melanoma. Related to Fig 1.

Figure EV1

  1. Genomic alterations and 36 tumor‐promoting genes identified in Fig 1. BRAF, NRAS, and NF1 have been added to the list of tumor‐promoting genes according to melanoma classification (Akbani et al, 2015). Analyses were performed using the webtool available at www.cbioportal.org.
  2. Birinapant, an inhibitor of BIRC proteins (BIRC3 and BIRC2), decreased cell density (SKMel28R cells, Birinapant 100 nM, 96 h).
  3. Birinapant, an inhibitor of BIRC proteins (BIRC3 and BIRC2), decreased cell density (Me1402 cells, Birinapant 100 nM, 96 h).

Data information: Each histogram represents the mean ± s.d. from three independent experiments. Bilateral Student test (with non‐equivalent variances) **P < 0.01.

Source data are available online for this figure.