Figure 1.

Structural formulas of L5P and L5P-Aq (A). The amino-acid residues belong to the L-series, unless otherwise specified. The N-ter and the C-ter moieties are indicated in green and red, respectively. Physico-chemical characterization of the purified synthetic L5P-Aq by RP-HPLC (B) and MS (C). (B) Detection is performed by UV at 230 nm (milli-absorption units). Purity is indicated in % area-under-the-curve. Retention time is indicated above the peak in min. (C) Mass/charge values in daltons: m/z 464.773 [M+2H]²⁺ (calcd 464.774), m/z 475.754 [M+H+Na]²⁺ (calcd 475.765), m/z 928.555 [M+H]⁺ (calcd 928.540), m/z 950.514 [M+Na]⁺ (calcd 950.522). See Supplementary Figure 1 for NMR spectra.