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Self-assembling of hyaluronic acid (HA) NGs functionalized with cholesteryl groups. (A) Scheme of nanoscaffold design, protein loading and administration. (B) Protein-hosting capacity in the proposed NGs, using different payloads: rhGH (a), EPO (b), lysozyme (c) and exendin-4 (d). Adapted with permission from Nakai et al. [105]. Copyright (2012) WILEY-VCH Verlag GmbH and Co. KGaA.
