Table 2.

Hypermethylation of APC promoters associated with prognosis in pancreatic cancer.

CpG site	Position	APC promoter	High (n)	Low (n)	p value	Prognosis	HR	95%CI
cg15020645	112,073,769	1a	138	46	0.012	harmful	0.544	(0.331;0.895)
cg24332422	112,073,686	1a	138	46	0.024	harmful	0.580	(0.352;0.954)
cg12534150	112,073,613	1a	46	138	0.0025	harmful	0.489	(0.314;0.761)
cg21634602	112,073,570	1a	46	138	0.001	harmful	0.474	(0.310;0.725)
cg02511809	112,073,544	1a	92	92	0.013	harmful	0.596	(0.395;0.899)
cg23938220	112,073,538	1a	46	138	0.021	harmful	0.582	(0.372;0.908)
cg20311501	112,073,502	1a	138	46	0.018	harmful	0.573	(0.354;0.926)
cg03667968	112,073,438	1a	46	138	0.035	harmful	0.611	(0.392;0.951)
cg16970232	112,073,433	1a	138	46	0.023	harmful	0.582	(0.357;0.949)
cg14479889	112,073,426	1a	95	89	0.039	harmful	0.654	(0.436;0.980)
cg11613015	112,073,406	1a	66	118	0.0028	harmful	0.526	(0.348;0.797)
cg22035501	112,073,398	1a	71	113	0.019	harmful	0.608	(0.403;0.917)
cg14511739	112,073,373	1a	75	109	0.021	harmful	0.617	(0.411;0.925)
cg08571859	112,073,350	1a	138	46	0.073	harmful	0.664	(0.420;1.052)
cg00577935	112,073,348	1a	92	92	0.049	harmful	0.668	(0.446;0.998)
cg04226363	112,043,716	1b	46	138	0.098	protective	1.504	(0.910;2.487)
cg25922032	112,043,407	1b	92	92	0.094	harmful	0.711	(0.477;1.060
cg08512345	11,204,3275	1b	78	106	0.065	harmful	0.680	(0.454;1.019)
cg26660754	112,043,194	1b	46	138	0.21	protective	1.353	(0.827;2.212)
cg18536802	112,043,188	1b	92	92	0.41	protective	1.185	(0.794;1.767)
cg08934600	112,043,158	1b	138	46	0.34	protective	1.245	(0.799;1.938)
cg01528425	112043137	1b	87	97	0.52	protective	1.142	(0.765;1.704)
cg18315896	112043131	1b	46	138	0.33	harmful	0.797	(0.508;1.252)
cg16481008	112043117	1b	80	104	0.05	protective	1.502	(0.993;2.273)
cg11057897	112042966	1b	138	46	0.28	harmful	0.781	(0.494;1.235)

HR, hazard ratio; CI, confidence interval.