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. Author manuscript; available in PMC: 2021 May 7.
Published in final edited form as: Sci Signal. 2019 Dec 3;12(610):eaav5918. doi: 10.1126/scisignal.aav5918

Fig. 10. Dermal fibroblasts from KI mice show no changes in the localization and abundance of 5-lipoxygenase.

Fig. 10.

(A) Immunofluorescence showing 5 - LO in pDFs from WT and cPLA2α KI mice. Scale bar, 40 μm. (B) Immunoblotting and quantification of 5 - LO in pDFs from WT and KI mice. (C) Immunoblotting and quantification of COX-1 and COX-2 in WT, KI, and KO pDFs. Data shown are means ± SD, n = 5–6 cell isolates per genotype (3–4 mice per genotype were used to generate the cell isolates) for confocal microscopy, n = 3 cell isolates per genotype (3 mice per genotype were used to generate the cell isolates) for immunoblot analysis, *P< 0.05, **P< 0.01, ***P< 0.001, ****P< 0.0001.