Table 1.

Assessments and timepoints

Study timepoints	Prescreen ing	Baseline	Day 1	Day 2	Day 3	Day 4	Day 5	Days 5–8	Days 5–28 (as applicable)	Day 28
Prescreening	X
Informed consent		X
Eligibility criteria		X
Eligibility review if change in health information			X
Randomisation/treatment allocation		X
Baseline case report form		X
Nose swab collection (if child remains unwell)			X	X	X	X	X
Nose swab return								X
Intervention arm—HS drops			X	X	X	X	X		X
Daily diary			X	X	X	X	X		X
Adverse events			X	X	X	X	X		X
End of illness diary
Satisfaction questionnaire
Return of diaries									X
Day 28 wheeze question										X

HS, hypertonic saline.