Table 2.
Most commonly reported cardiovascular complications in clinical studies
| Adult population | Pediatric population | |
|---|---|---|
| Electrocardiogram | Nonspecific ST changes (n = 4) | Arrhythmia of any kind (n = 1) |
| Sinus tachycardia (n = 2) | ||
| First degree AV-block (n = 2) | ||
| Sinus bradycardia (n = 2) | ||
| Cardiac biomarkers | Creatine kinase MB (n = 6) | Troponin (TnT/TnI) (n = 2) |
| NT-proBNP (n = 6) | NT-proBNP (n = 2) | |
| Troponin (TnT/TnI) (n = 5) | Creatine kinase MB (n = 1) | |
| Myoglobin (n = 4) | Myoglobin (n = 1) | |
| Cystatin C (n = 3) | Cystatin C (n = 1) | |
| H-type fatty acid binding protein (n = 2) | H-type fatty acid binding protein (n = 1) | |
| MR-proANP (n = 1) | ||
| Echocardiography | LV ejection fraction (n = 4) | LV ejection fraction (n = 1) |
| LV end-diastolic dimension (n = 3) | LV end-diastolic dimension (n = 1) | |
| Diastolic dysfunction (n = 2) | ||
| LV end-systolic dimension (n = 1) |
AV = atrioventricular; LV = left ventricular; MB = myocardial band; MR-proANP = MR–pro-atrial natriuretic peptide; NT-proBNP = N-terminal–pro-brain natriuretic peptide; TnT/I = troponin T and I.