Table 6.
Sample genotyping data table for late recurrences from an antimalarial efficacy trial, showing band lengths, locus-by-locus comparisons, and final classification
| Sample ID | msp1 | msp2 | msp1 call | msp2 call | glurp call | Final classification | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Day | K1 | Mad20 | RO33 | FC27 | 3D7 | Glurp | |||||
| 001 | 0 | – | 240 | – | – | 300 | 500 | R | R | R | R |
| 001 | 21 | – | 240 | – | – | 300 | 500 | ||||
| 002 | 0 | – | 210/190 | 215 | 200 | – | 900/1,000 | R | R | R | R |
| 002 | 21 | – | 190 | – | 200 | – | 1,000 | ||||
| 003 | 0 | – | 200 | – | 250 | – | 600 | R | R | R | R |
| 003 | 28 | – | 200/220 | 215 | 250 | 420 | 600 | ||||
| 004 | 0 | – | 240 | 215 | 250 | 300/400 | 1,000 | R | R | R | R |
| 004 | 21 | 210 | 210 | 215 | 350 | 400 | 500/1,000 | ||||
| 005 | 0 | 200 | 210 | 215 | 300 | 300 | 1,000 | R | NI | R | NI |
| 005 | 14 | – | 190/220 | 215 | 280 | 350 | 1,000 | ||||
| 006 | 0 | – | 210 | – | 300 | – | 1,000 | NI | NI | NI | NI |
| 006 | 28 | – | 220 | – | – | 350 | 900 | ||||
Samples correspond to band patterns shown in Figure 1. R = recrudescence; NI = new infection. Recrudescences were defined following the standard WHO protocol, where the presence of at least one shared allele (i.e., band) at all successfully genotyped loci was sufficient for evidence of recrudescence. Boldface indicates a match between the day 0 sample and the day of recurrent parasitemia sample.