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. 2021 Apr 23;11:630706. doi: 10.3389/fonc.2021.630706

Table 2.

Univariate analysis of the prognostic factors in ccRCC patients using a Cox regression model.

Parameters OS Univariate analysis Multivariate analysis
HR(95%CI) p HR(95%CI) p
HCST expression High vs. Low 1.853(1.210–2.839) 0.004 1.630 (1.042–2.552) 0.032
Age ≥65 vs. <60 1.370(0.908–2.067) 0.133 1.371 (0.893–2.105) 0.149
Female vs. male 1.013(0.666–1.541) 0.951 1.099 (0.709–1.704) 0.673
TMN stage III/IV vs. I/II 3.676(2.366–5.711) <0.001 1.295 (0.511–3.280) 0.278
Grade G1/2 vs. G3/4 2.629(1.655–4.176) <0.001 1.829 (1.115–3.001) 0.017
Invasion depth T1/2 vs. T3/4 3.311(2.167–5.058) <0.001 1.594 (0.699–3.634) 0.268
Lymph node metastasis 2.932(1.516–2.839) <0.001 1.273 (0.629–2.574) 0.502
Distant metastasis 4.073(2.634–6.300) 0.001 2.634 (1.562–4.442) <0.001

CI, confidence interval.