Table 4.
Treatment (Trt) | HIM | P-value | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CON | GLU | SEM | 0 | 3 | 6 | 9 | 12 | 15 | 18 | 21 | 24 | SEM | Trt | HIM | Trt × HIM | |
Whole blood | ||||||||||||||||
O2, mmol/L | 4.30 | 4.23 | 0.23 | 4.30 | 4.15 | 4.14 | 4.23 | 4.26 | 4.40 | 4.36 | 4.12 | 4.02 | 0.28 | 0.72 | 0.22 | 0.02 |
CO2, mmol/L | 31.3 | 30.6 | 0.69 | 30.0 | 30.1 | 29.1 | 29.9 | 29.0 | 29.8 | 30.0 | 30.5 | 30.8 | 0.65 | 0.87 | 0.19 | 0.13 |
pH | 7.51 | 7.49 | 0.01 | 7.50ab | 7.48b | 7.50ab | 7.52a | 7.52a | 7.51ab | 7.48b | 7.51ab | 7.50ab | 0.01 | 0.30 | 0.04 | 0.51 |
Na+, mmol/L | 140 | 140 | 0.51 | 139 | 140 | 141 | 140 | 141 | 140 | 139 | 140 | 140 | 0.58 | 0.44 | 0.25 | 0.58 |
K+, mmol/L | 3.90 | 4.06 | 0.06 | 4.07 | 4.05 | 4.19 | 3.95 | 3.89 | 3.89 | 3.95 | 3.94 | 3.90 | 0.08 | 0.08 | 0.08 | 0.18 |
Ca++, mmol/L | 1.18 | 1.21 | 0.03 | 1.17 | 1.18 | 1.18 | 1.18 | 1.20 | 1.21 | 1.21 | 1.21 | 1.21 | 0.02 | 0.39 | 0.18 | 0.70 |
Cl−, mmol/L | 103 | 103 | 0.66 | 103 | 103 | 103 | 103 | 103 | 102 | 102 | 102 | 102 | 0.58 | 0.68 | 0.18 | 0.85 |
Glucose, mmol/L | 4.84 | 4.88 | 0.12 | 4.57 | 4.68 | 4.76 | 4.95 | 4.78 | 5.14 | 4.92 | 5.11 | 4.84 | 0.18 | 0.84 | 0.16 | 0.56 |
l-Lactate, mmol/L | 1.14b | 1.48a | 0.07 | 1.74a | 1.39b | 1.29bc | 1.11bc | 1.26bc | 0.99c | 1.29bc | 1.39b | 1.34b | 0.11 | 0.003 | 0.001 | 0.64 |
Plasma | ||||||||||||||||
Glucose, mmol/L | 5.52 | 5.40 | 0.14 | 5.30 | 5.36 | 5.30 | 5.65 | 5.41 | 5.81 | 5.48 | 5.45 | 5.40 | 0.21 | 0.58 | 0.37 | 0.81 |
l-Lactate, mmol/L | 1.15b | 1.53a | 0.07 | 1.85a | 1.43ab | 1.35bc | 1.11bc | 1.29bc | 1.02c | 1.31bc | 1.34bc | 1.37b | 0.12 | 0.002 | 0.002 | 0.43 |
Urea, umol/L | 3.32 | 3.47 | 0.34 | 3.18 | 3.21 | 3.22 | 3.30 | 3.42 | 3.65 | 3.63 | 3.52 | 3.41 | 0.27 | 0.77 | 0.49 | 0.94 |
TG, umol/L | 0.24 | 0.25 | 0.02 | 0.30 | 0.28 | 0.25 | 0.21 | 0.21 | 0.21 | 0.24 | 0.25 | 0.27 | 0.03 | 0.82 | 0.32 | 0.15 |
NEFA, µekv/L | 574 | 524 | 75.2 | 560abc | 690ab | 741a | 592abc | 492abc | 438bc | 427c | 492abc | 470bc | 86.8 | 0.66 | 0.02 | 0.65 |
Insulin, ng/L | 56.2 | 65.1 | — | 34.4cd | 30.1d | 27.4d | 51.3c | 66.3bc | 101ab | 103ab | 92.3ab | 118a | — | 0.47 | <0.001 | 0.97 |
a,bLeast squares treatment means with different superscript letters differ significantly (P < 0.05).