Table 3.
Snus use | ||
---|---|---|
Outcome and model (total number) | Nonusers | Users |
Myocardial infarction (N = 20,501) | ||
Total number of cases | 852 | 21 |
Age and sex-adjusted model | 1.00 (reference) | 1.35 (0.87–2.10) |
Multivariable model 1† | 1.00 (reference) | 1.36 (0.87–2.11) |
Heart failure (N = 21,130) | ||
Total number of cases | 1066 | 14 |
Age and sex-adjusted model | 1.00 (reference) | 1.04 (0.61–1.78) |
Multivariable model 1† | 1.00 (reference) | 0.92 (0.54–1.57) |
Atrial fibrillation (N = 19,852) | ||
Total number of cases | 2193 | 43 |
Age and sex-adjusted model | 1.00 (reference) | 1.33 (0.98–1.81) |
Multivariable model 1† | 1.00 (reference) | 1.29 (0.95–1.75) |
Total stroke* (N = 20,620) | ||
Total number of cases | 1160 | 24 |
Age and sex-adjusted model | 1.00 (reference) | 1.57 (1.04–2.37) |
Multivariable model 1† | 1.00 (reference) | 1.53 (1.02–2.32) |
Total ischemic stroke (N = 20,620) | ||
Total number of cases | 957 | 21 |
Age and sex-adjusted model | 1.00 (reference) | 1.69 (1.09–2.63) |
Multivariable model 1† | 1.00 (reference) | 1.65 (1.06–2.57) |
CVD mortality (N = 18,189) | ||
Total number of deaths | 780 | 15 |
Age and sex-adjusted model | 1.00 (reference) | 1.70 (1.01–2.87) |
Multivariable model 1† | 1.00 (reference) | 1.58 (0.94–2.67) |
CI confidence interval, HR hazard ratio. Participants with a diagnosis of the corresponding CVD before the start of a follow-up, were excluded from the disease-specific analysis. In the analysis of overall CVD mortality, those who were diagnosed with CVD before the start of a follow-up were also excluded
*Includes ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, and undefined type of stroke
†The Cox proportional hazards regression model was adjusted for age (underlying time scale), sex (as a stratification variable), education, alcohol consumption, walking/bicycling, and exercise