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CD4+ T cell proliferation and absolute counts. Shown are levels of Ki67 expression in CD4+ T cells (A) and absolute counts of CD4+ T cells (B) in the peripheral blood of groups treated with CD8α depletion plus AZD5582, AZD5582 only, or CD8α depletion only. Data are expressed as the fold changes from baseline levels after intervention. Statistical significance was determined with a two-sided Mann-Whitney U test. Horizontal lines represent the medians.
