TABLE 3.

Tideglusib drug levels in plasma following intravenous dosing^a

Time after tideglusib infusion	Level (ng/ml)
	Tideglusib						Control
	31041	31096	31100	31831	31098	31132	31293	31315	31500	31153	31254
0 min	<5	<5	<5	<5	<5	<5	<5	<5	<5	<5	<5
5 min	17,719	17,749	<5	14,675	14,693	9,536	<5	<5	<5	<5	<5
15 min	2,875	1,998	227	1,380	1,587	1,740	<5	<5	<5	<5	<5
60 min	40	32	<5	32	25	26	<5	<5	<5	<5	<5
24 h	<5	<5	<5	<5	<5	<5	<5	<5	<5	<5	<5
48 h	<5	<5	<5	<5	<5	<5	<5	<5	<5	<5	<5
7 days	<5	<5	<5	<5	<5	<5	<5	<5	<5	<5	<5

^aSamples were collected at the indicated times following i.v. administration of tideglusib at 5 mg/kg. Animals are identified by five-digit numbers. The limit of detection was 5 ng/ml.