Fig. 2.

DHEA-shaped gut microbiota reproduced glucose intolerance, polycystic ovaries and reproductive hormone disorders in FMT recipients. a Timeline for animal experiments in FMT recipients. Yellow bars represent normal feeding with standard chow and non-acidified drinking water. Other treatments are indicated in the schema. b Bodyweight, c FBG, d GTT, e area under the curve of GTT, f typical oestrous cycles and g H&E staining of typical ovaries. * indicates CL, and cyst-like follicles are indicated by #. Black arrows indicate normal granulosa cell layers. Red arrows indicate attenuated granulosa cell layers. Scale bar = 1000 μm (left) and 200 μm (right). h  serum TT levels, i serum SHBG levels, j FAI, k serum LH levels, l serum FSH levels and m LH:FSH ratio. Data are given as mean ± SEM. n = 6 rats per group. * p < 0.05; ** p < 0.01