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. 2021 May 7;44:437–444. doi: 10.1016/j.clnesp.2021.04.020

Table 5.

HDL c level and Tg/HDL c ratio as risk factors adjusted to age and gender for the requirement of invasive mechanical ventilation in patients with COVID-19.

Variable Sig Chi2 R2 Nagelkerke Coefficient B SE OR Multivariate (CI 95%) p
Step 1 HDL c ≤ 35 mg/dL 2.619 1.134 13.716 (1.485–126.654) 0.021
Tg/HDL c ≥ 7.45 <0.001 0.542 2.469 0.951 11.815 (1.832–76.186) 0.009
Age −0.064 0.035 0.938 (0.876–1.005) 0.069
Gender −0.246 0.873 0.782 (0.141–4.325) 0.778
Constant 1.858 2.220 6.409 0.403
Step 2 HDL c ≤ 35 mg/dL 2.633 1.129 13.916 (1.523–127.171) 0.020
Tg/HDL c ≥ 7.45 <0.001 0.541 2.463 0.952 11.742 (1.817–75.854) 0.010
Age −0.064 0.035 0.938 (0.876–1.006) 0.071
Constant 1.694 2.162 5.440 0.433

Table 5: The value of p was derived from Multivariate logistic regression analysis with successive steps backward (conditional) method. Statistical significance p values are shown in bold (p < 0.05).

Abbreviations: HDL c, High-density lipoprotein cholesterol; LDL c, Low-density lipoprotein cholesterol; OR, odds ratio; SD, standard deviation; Tg/HDL c, Triglyceride/High-density lipoprotein cholesterol ratio.