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. Author manuscript; available in PMC: 2021 May 7.
Published in final edited form as: Biochemistry. 2019 Sep 9;58(38):3990–4002. doi: 10.1021/acs.biochem.9b00659

Figure 2. Inhibition of COX-2 Homodimer Constructs by Celebrex.

Figure 2.

Inhibition assays were performed as described in Experimental Procedures to assess (A) instantaneous and (B) time-dependent inhibition of L531F, L531N, and native huCOX-2 homodimer constructs by Celebrex. Associated dose-response curves are plotted to the right of each bar graph. Values represent the average of triplicate measurements ± the standard deviation of the mean.