Table 2.

Demographic and clinical data for amyloid positive (PiB+) and amyloid negative (PiB-) individuals.

Group	PiB+ (MCI/HCS)	PiB- (HCS)	p-value
Diagnostic Group	6/6	15	n. a.
Global-β-amyloid (Mean/SD)	1.71 (0.3)	1.1 (0.03)	<0.001
ApoE ε4 carrier	4/3	2	n. a.
Gender (F, M)	3/3, 3/3	4/11	n. a.
Age in years (Mean/SD)	74.2 (8.1)	71.1 (3.9)	>0.05
Level of education (years)	12.5 (2.0)	15.3 (3.1)	0.014
Cognitive variables
MMSE, /30	28.7 (1.3)	29.6 (0.6)	0.04
DS (forward)	−0.39 (0.7)	0.15 (0.8)	0.10
DS (backward)	0.06 (0.8)	0.59 (1.2)	0.22
Trail making (B/A)	−0.52 (1.2)	−0.45 (1.1)	0.90
Letter fluency	0.09 (1.7)	−0.06 (0.9)	0.80
Category fluency	0.52 (1.9)	0.11 (0.8)	0.46
Number of figures	−0.41 (0.8)	0.44 (1.1)	0.04
Stroop Interference	−0.35 (1.0)	0.58 (0.5)	0.007
Boston naming	−0.25 (1.1)	0.14 (0.7)	0.27
VLMT learning	−0.64 (1.5)	0.67 (0.8)	0.009
VLMT recognition	−2.19 (2.0)	0.22 (0.7)	<0.001
VLMT delayed recall	−1.51 (1.6)	0.28 (0.8)	0.001
CERAD recall	−0.76 (1.5)	0.70 (1.0)	0.009
CERAD word learning	−0.13 (1.5)	0.85 (1.2)	0.08

Groups differ in Aβ deposition (p < 0.001), APOEε4+ presence, gender [female (F)/male (M) distribution], and level of education (p = 0.002). Cognitive variables are z-transformed raw scores means and standard deviations (SD) except for MMSE. PiB+ showed significantly lower performance for MMSE as well as for the Stroop interference task, and for some of the memory related tests (VLMT and CERAD). MMSE, Mini mental status examination.

Bold values indicate significant group differences.