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. 2019 Sep 12;23(9):601–609. doi: 10.1089/gtmb.2019.0085

Table 2.

Single Nucleotide Polymorphism of Blood Vessel Epicardial Substance in Tetralogy of Fallot Samples

SNP Tissue Nucleotide Genotype Exon Protein MAF in TOF MAF in NCBI
Blood (n = 57) Tissue (n = 89)
rs143510978 1 0 c.408T>G +/− Exon4 p.R136H G = 1/146 = 0.0034 G = 0.0022/11 (1000 Genomes)
rs751152136 0 1 c.195T>C +/− Exon2 p.H65H A = 1/146 = 0.0034 C = 0.000008/1 (ExAC)
rs2275289 4 6 c.385C>T +/− Exon4 p.R129W T = 10/146 = 0.0351 T = 0.0050 (1000 Genomes)
rs183390165 0 1 c.1068C>T +/− Exon8 p.V356V A = 1/146 = 0.0034 A = 0.0004/2 (1000 Genomes)

1000 Genomes, 1000 Genomes Project; ExAC, Exome Aggregation Consortium; +/−, heterozygote.

TOF, Tetralogy of Fallot; MAF, minor allelic frequencies; SNP, single nucleotide polymorphism.