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CS-6 suppresses RANKL-mediated marker genes expression in osteoclastogenesis. (A, B) The relative mRNA expression of OC-related genes (c-Fos, TRAP, CTSK, MMP-9, DC-STAMP, and β3-integrin) following CS-6 treatment was measured by qRT-PCR in the early (A) and late (B) stages of stimulation. Values presented as the mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
