FIG 3.

Cell-associated SHIV RNA and DNA in total PBMCs and rectal lymphocytes in SHIV.C.CH848-infected rhesus macaques on antiretroviral therapy. (a to c) Changes in levels of US SHIV RNA (a), total SHIV DNA (b), and proviral SHIV DNA (c) in rectal lymphocytes. (d to f) Levels of US SHIV RNA, total SHIV DNA, and proviral SHIV DNA in PBMCs at pretreatment (month 5 p.i.) and in cART-treated and untreated groups at 6 months. Error bars indicate SEM. *, P < 0.01 (paired t test was used to compare groups); #, P < 0.01 (comparison between pretreatment [month 5 p.i.] and after treatment in rectal tissue at different time points); ##, P < 0.05 (comparison with pretreatment or untreated controls in blood).