FIG 4.
Viral Env evolution in SHIV.C.CH848-infected macaques. Shown are amino acid highlighter plots showing single-genome env sequences from SHIV.C.CH848-infected RM at 5 months postinfection. Nonsynonymous substitutions compared to the TF sequence are indicated by a red line, and deletions are shown as a black line. Each horizontal line shows one single-genome sequence. Two common sites of selection pressure (Env residues 3/4 and 195) were identified in infected animals.