TABLE 1.
Plasma neutralization ID50 titers of SHIV.C.CH848-infected rhesus macaquesa
| Plasma ID |
ID50 at: |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 5 mo postinfection |
15 mo postinfection |
2 yrs postinfection |
||||||||
| CH848 (C) | CH848 (C) | CH848 (C) | Du156.12 (C) | ZM109.4 (C) | Q23.17 (A) | BG505 (A) | Yu2 (B) | JR-FL (B) | AD17 (B) | |
| 1 (cART) | <20 | <25 | 27 | ND | ND | ND | ND | ND | ND | ND |
| 2 (cART) | 57 | 97 | 214 | ND | ND | ND | ND | ND | ND | ND |
| 3 (cART) | 96 | 272 | 316 | <25 | <25 | <25 | <25 | <25 | <25 | <25 |
| 4 (cART) | 34 | 508 | 1,350 | <25 | 28 | <25 | <25 | <25 | <25 | <25 |
| 5 (cART) | 57 | 100 | 472 | <25 | <25 | <25 | <25 | <25 | <25 | <25 |
| 6 | 342 | 215 | 113 | <25 | <25 | <25 | <25 | <25 | <25 | <25 |
| 7 | 149 | 554 | 392 | <25 | 51 | 336 | 26 | <25 | 26 | <25 |
| 8 | 21 | 183 | 347 | <25 | <25 | 36 | <25 | <25 | <25 | <25 |
| 9 | 22 | 267 | ND | ND | ND | ND | ND | ND | ND | ND |
| 10 | 48 | 369 | 630 | <25 | <25 | <25 | <25 | <25 | <25 | <25 |
a
Plasma samples from SHIV.C.CH848-infected RMs at 5 months, 15 months, and 2 years postinfection were tested against a panel of autologous and heterogeneous viruses in TZM-bl cells. Clades are indicated in parentheses. Potency of 50 to 99 is indicated by italics; 100 to 999, underlining; and ≥1,000, underlining and boldface type. ND, not detected.