Table 2.
Weekly ventilatory parameters of the 963 patients categorized by weaning outcome.
| All | Successful weaning (–) | Successful weaning (+) | p-value | |
|---|---|---|---|---|
| N = 963 | N = 424 | N = 539 | ||
| FiO2 (%) | ||||
| Week 4 | 35.1 ± 5.6 | 36.4 ± 6.1 | 34.1 ± 5.0 | <0.01 |
| Week 5 | 34.9 ± 7.0 | 36.9 ± 8.8 | 33.4 ± 4.7 | <0.01 |
| Week 6 | 35.1 ± 8.6 | 37.6 ± 11.4 | 33.1 ± 4.8 | <0.01 |
| Week 7 | 35.6 ± 10.3 | 38.6 ± 13.4 | 33.2 ± 6.2 | <0.01 |
| Week 8 | 35.8 ± 11.1 | 39.2 ± 14.5 | 33.2 ± 6.3 | <0.01 |
| Week 9 | 36.0 ± 12.0 | 39.7 ± 15.7 | 33.2 ± 6.8 | <0.01 |
| PEEP (cmH2O) | ||||
| Week 4 | 5.8 ± 1.6 | 6.0 ± 1.7 | 5.6 ± 1.5 | <0.01 |
| Week 5 | 5.6 ± 1.4 | 5.9 ± 1.6 | 5.4 ± 1.1 | <0.01 |
| Week 6 | 5.6 ± 1.3 | 5.9 ± 1.5 | 5.3 ± 1.0 | <0.01 |
| Week 7 | 5.5 ± 1.3 | 5.8 ± 1.6 | 5.2 ± 0.9 | <0.01 |
| Week 8 | 5.5 ± 1.3 | 5.8 ± 1.6 | 5.2 ± 0.9 | <0.01 |
| Week 9 | 5.5 ± 1.3 | 5.9 ± 1.6 | 5.2 ± 0.9 | <0.01 |
| Ppeak (cmH2O) | ||||
| Week 4 | 21.7 ± 4.9 | 23.2 ± 4.9 | 20.5 ± 4.5 | <0.01 |
| Week 5 | 20.9 ± 5.6 | 23.2 ± 6.3 | 19.1 ± 4.1 | <0.01 |
| Week 6 | 20.6 ± 5.4 | 23.0 ± 5.8 | 18.6 ± 4.1 | <0.01 |
| Week 7 | 20.6 ± 5.7 | 23.4 ± 6.3 | 18.4 ± 4.1 | <0.01 |
| Week 8 | 20.7 ± 5.79 | 23.7 ± 6.5 | 18.3 ± 4.0 | <0.01 |
| Week 9 | 20.8 ± 6.0 | 24.0 ± 6.6 | 18.3 ± 3.9 | <0.01 |
| Pmean (cmH2O) | ||||
| Week 4 | 10.6 ± 2.4 | 11.3 ± 2.5 | 10.2 ± 2.3 | <0.01 |
| Week 5 | 10.4 ± 2.5 | 11.3 ± 2.9 | 9.6 ± 1.9 | <0.01 |
| Week 6 | 10.3 ± 2.6 | 11.4 ± 3.0 | 9.4 ± 1.9 | <0.01 |
| Week 7 | 10.3 ± 2.7 | 11.5 ± 3.2 | 9.3 ± 1.8 | <0.01 |
| Week 8 | 10.3 ± 2.9 | 11.6 ± 3.4 | 9.2 ± 1.8 | <0.01 |
| Week 9 | 10.3 ± 2.9 | 11.7 ± 3.5 | 9.2 ± 1.7 | <0.01 |
| VT/PBW (ml/kg) | ||||
| Week 4 | 9.0 ± 1.9 | 9.1 ± 1.9 | 8.9 ± 2.0 | 0.12 |
| Week 5 | 8.7 ± 2.0 | 8.9 ± 2.0 | 8.5 ± 2.0 | <0.01 |
| Week 6 | 8.6 ± 2.1 | 8.9 ± 2.0 | 8.3 ± 2.1 | <0.01 |
| Week 7 | 8.6 ± 2.2 | 9.0 ± 2.2 | 8.3 ± 2.1 | <0.01 |
| Week 8 | 8.6 ± 2.2 | 9.0 ± 2.3 | 8.3 ± 2.1 | <0.01 |
| Week 9 | 8.6 ± 2.3 | 9.1 ± 2.4 | 8.3 ± 2.1 | <0.01 |
| Respiratory rate (/min) | ||||
| Week 4 | 18.9 ± 3.2 | 19.0 ± 3.3 | 18.9 ± 3.2 | 0.44 |
| Week 5 | 19.4 ± 3.2 | 19.3 ± 3.4 | 19.4 ± 3.1 | 0.66 |
| Week 6 | 19.6 ± 3.2 | 19.4 ± 3.5 | 19.7 ± 3.0 | 0.26 |
| Week 7 | 19.6 ± 3.3 | 19.5 ± 3.6 | 19.7 ± 3.1 | 0.38 |
| Week 8 | 19.6 ± 3.4 | 19.4 ± 3.7 | 19.7 ± 3.1 | 0.22 |
| Week 9 | 19.5 ± 3.3 | 19.2 ± 3.6 | 19.6 ± 3.0 | 0.07 |
| Minute ventilation (L/min) | ||||
| Week 4 | 9.3 ± 2.5 | 9.6 ± 2.1 | 9.1 ± 2.8 | <0.01 |
| Week 5 | 9.2 ± 2.5 | 9.6 ± 2.4 | 8.8 ± 2.6 | <0.01 |
| Week 6 | 9.1 ± 2.7 | 9.6 ± 2.6 | 8.7 ± 2.7 | <0.01 |
| Week 7 | 9.1 ± 2.9 | 9.6 ± 2.7 | 8.6 ± 2.9 | <0.01 |
| Week 8 | 9.0 ± 2.9 | 9.5 ± 2.9 | 8.6 ± 2.9 | <0.01 |
| Week 9 | 9.0 ± 3.0 | 9.6 ± 3.0 | 8.6 ± 2.9 | <0.01 |
Data were presented as mean ± standard deviation.
FiO2, fraction of inspired oxygen; PEEP, positive end-expiratory pressure; Ppeak, peak inspiratory pressure; Pmean, mean airway pressure; VT/PBW, tidal volume per predicted body weight.