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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Pediatr Res. 2020 Feb 13;88(1):100–109. doi: 10.1038/s41390-020-0784-y

Table 3.

Distribution of ACEs and ACE groupings, rates and odds of persistent emotional, developmental and behavioral problems in children and adolescents.

N (%)a,b Persistent EDB problemsa Odds ratios (95% CI)a,c,d
Unadjusted Adjustede Adjustede for all ACEs
Overall 6.5 (5.9, 7.1)
 ACE 1: Sometimes or very often it has been very hard to get by on your family’s income (e.g., it was hard to cover the basics like food or housing) 5449 (24.7) 10.7 (9.2, 12.3) 2.2 (1.8, 2.7) 2.1 (1.7, 2.6) 1.6 (1.3, 2.0)
 ACE 3: Lived with a parent or guardian who got divorced or separated after they were born 7638 (29.6) 10.7 (9.3, 12.0) 2.4 (2.0, 2.9) 2.2 (1.8, 2.7) 1.3 (1.1, 1.7)
 ACE 4: Lived with a parent or guardian who died 1014 (4.2) 13.1 (9.7, 16.5) 2.3 (1.7, 3.1) 1.9 (1.4, 2.7) 1.3 (0.9, 1.9)
 ACE 5: Lived with a parent or guardian who served time in jail or prison in their lifetime 1882 (9.1) 15.0 (12.1, 17.9) 3.0 (2.3, 3.8) 2.7 (2.1, 3.6) 1.4 (1.0, 1.9)
 ACE 6: Saw or heard any parents, guardians, or any other adults in [his/her] home slap, hit, kick, punch, or beat each other up 1490 (6.4) 18.3 (14.4. 22.1) 3.7 (2.8, 4.9) 3.3 (2.5, 4.4) 1.2 (0.8, 1.7)
 ACE 7: Was the victim of violence or witnessed any violence in [his/her] neighborhood 1018 (4.5) 23.6 (17.6, 29.5) 5.1 (3.6, 7.2) 4.8 (3.4, 6.7) 2.2 (1.4, 3.5)
 ACE 8: Lived with anyone who was mentally ill or suicidal, or severely depressed for more than a couple of weeks 2639 (8.7) 19.2 (16.1, 22.3) 4.2 (3.4, 5.3) 4.0 (3.2. 5.0) 2.2 (1.7, 2.9)
 ACE 9: Lived with anyone who had a problem with alcohol or drugs 2969 (10.5) 16.6 (13.7, 19.5) 3.5 (2.8, 4.5) 3.4 (2.7, 4.3) 1.4 (1.1, 1.8)
 ACE 10: Was treated or judged unfairly because of [his/her] race or ethnic group 1034 (4.8) 14.2 (9.5, 18.8) 2.5 (1.7, 3.7) 2.6 (1.7, 3.7) 1.3 (0.9, 1.9)
N (%)a,b Persistent EDB
problemsa
Odds ratios (95% CI)a,d
Unadjusted Adjustede
Dose–response relationship
 Among all nine ACEs
  REF: No ACEs 16,572 (49.7) 3.5 (2.9, 4.0)
  1 ACE 6777 (25.0) 5.6 (4.6, 6.6) 1.6 (1.3, 2.1) 1.7 (1.3, 2.2)
  2 ACEs 3013 (12.4) 8.8 (7.0, 10.6) 2.7 (2.0, 3.5) 2.8 (2.0, 3.7)
  3 ACEs 1439 (5.6) 11.7 (9.1, 14.4) 3.7 (2.7, 5.0) 3.9 (2.8, 5.5)
  4+ ACEs 1649 (7.3) 22.4 (18.3, 26.6) 8.0 (6.0, 10.7) 8.6 (6.2, 11.9)
Comparability of ACE groups
 Among all nine ACEs
  REF: No ACEs 16,572 (49.7) 3.5 (2.9, 4.0)
  Any ACEs 12,878 (50.3) 9.5 (8.6, 10.5) 2.9 (2.4, 3.6) 2.8 (2.3, 3.5)
 Among all nine ACEs
  REF: No ACEs 16,572 (49.7) 3.5 (2.9, 4.0)
  1 ACE 6777 (25.0) 5.6 (4.6, 6.7) 1.6 (1.3, 2.1) 1.7 (1.3, 2.3)
  2 ACEs 3013 (12.4) 8.8 (7.0, 10.6) 2.7 (2.0, 3.5) 2.7 (2.0, 3.7)
  3+ ACEs 3088 (12.9) 17.8 (15.2, 20.4) 6.0 (4.7, 7.7) 6.4 (4.8, 8.5)
 Among FIVE ACEs which had significant independent effects
  REF: None of these five ACEs 17,430 (53.1) 3.6 (3.1, 4.2)
  1 ACE 7063 (27.1) 6.1 (5.1, 7.1) 1.7 (1.4, 2.2) 1.8 (1.4, 2.3)
  2 ACEs 3022 (12.0) 10.4 (8.5, 12.4) 3.1 (2.4, 4.0) 3.1 (2.3, 4.1)
  3 ACEs 1935 (7.8) 21.4 (17.6, 25.2) 7.2 (5.5, 9.5) 7.4 (5.4, 10.0)
 Among ACE 1 and ACE 3
  REF: Neither of these ACEs 18,935 (57.4) 4.3 (3.7, 4.9)
  1 ACE 7943 (30.8) 7.5 (6.5, 8.5) 1.8 (1.5, 2.2) 1.8 (1.4, 2.3)
  2 (both) ACEs 2572 (11.8) 14.9 (12.2, 17.7) 3.9 (3.0, 5.1) 3.8 (2.8, 5.2)
a

Weighted.

b

Within row.

c

Referent category: Those without that particular ACE.

d

Odds ratios in bold indicate statistical significance (p < 0.05).

e

Adjusted for: Sex, race/ethnicity, maximum household education, age, household size and income as % of poverty level (Caps: Min = 50, Max = 400).