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. 2021 May 7;2021(5):CD001150. doi: 10.1002/14651858.CD001150.pub4

Summary of findings 4. Topical oil versus another oil for preterm infants.

Topical oil versus another oil for preventing infection in preterm infants
Patient or population: preterm (< 37 weeks) and low birth weight (< 2500 g) infants
Settings: high‐income countries, and low‐ and middle‐income countries
Intervention: topical oil
Comparison: another topical oil
Outcomes Illustrative comparative risks* (95% CI) Relative effect
(95% CI) No of participants
(studies) Quality of the evidence
(GRADE) Comments
Assumed risk Corresponding risk
Routine skin care Topical oil
Invasive infection
until hospital discharge 0 per 1000 0 per 1000
(0 to 0) not estimable 64
(1) ⊕⊝⊝⊝
verylowa,b No events
Mortality until hospital discharge (or latest reported) 0 per 1000 0 per 1000
(0 to 0) not estimable 64
(1) ⊕⊝⊝⊝
verylowa,b No events
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval; RR: risk ratio.

aDowngraded one level due to serious risk of bias (caregivers and investigators not masked).
bDowngraded two levels due to serious imprecision. There were no events in either arm.