Strunk 2018.

Study characteristics
Methods	Randomised controlled trial.
Participants	Preterm infants < 30 weeks' gestation, postnatal age < 24 hours. Exclusions: infants with major congenital anomalies, or signs of pre‐existing skin infection.
Interventions	1. Topical coconut oil (5 mL/kg) twice daily: N = 36 2. Standard skin care (no emollient): N = 36 Intervention applied for up to 21 days.
Outcomes	Skin condition until day 21. Weight gain. Invasive infection. Necrotising enterocolitis (NEC). Mortality. Cognitive, language, motor or socio‐emotional delay assessed at 24 months (corrected age) using Bayley Scales of Infant Development (3rd Edition).
Notes	Setting: Neonatal Intensive Care Unit, Edward Memorial Hospital, Perth, Australia (2018).
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated
Allocation concealment (selection bias)	Low risk	Sealed, coded, opaque, serially‐numbered envelopes
Blinding of participants and personnel (performance bias) All outcomes	High risk	Unmasked parents and caregivers
Blinding of outcome assessment (detection bias) All outcomes	High risk	Unmasked clinicians and investigators
Incomplete outcome data (attrition bias) All outcomes	Low risk	Complete for in hospital outcomes (25% attrition for neurodevelopmental assessments)
Selective reporting (reporting bias)	Low risk	Unlikely
Other bias	Low risk	No evidence of baseline imbalance