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. 2021 May 7;100(18):e25900. doi: 10.1097/MD.0000000000025900

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Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Risk factor for severe clinical outcomes in the patients with COVID-19. Multivariate Cox proportional hazard model demonstrated CCIS is an independent risk factor for composite outcome (A) and mortality (B) after adjusting other risk factors. BMI = body mass index, BP = blood pressure, CCIS = age-adjusted Charlson comorbidity index score, CI = confidence interval, COVID-19 = coronavirus disease 2019.