Table 4.
Correlations between different parameters.
| Correlations | |||||||||||
| Final outcome | Evolution after TCZ | Serum C-reactive protein level before TCZ | d-dimer serum concentration | Serum ferritin level | Neutrophil to lymphocyte ratio | Platelet count | Serum IL-6 level after TCZ | Extubation | Serum IL-6 level before TCZ | IL-6 difference | |
| Final outcome | |||||||||||
| Pearson correlation | 1 | .890∗ | 0.206 | 0.085 | 0.097 | 0.084 | 0.052 | −0.114 | −.647∗ | −0.067 | −0.063 |
| Sig. (2-tailed) | 0.000 | 0.323 | 0.731 | 0.652 | 0.690 | 0.806 | 0.614 | 0.000 | 0.749 | 0.764 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
| Evolution after TCZ | |||||||||||
| Pearson correlation | .890∗ | 1 | 0.282 | 0.165 | 0.148 | 0.051 | −0.174 | −0.121 | −.657∗ | −0.105 | −0.044 |
| Sig. (2-tailed) | 0.000 | 0.173 | 0.499 | 0.491 | 0.810 | 0.405 | 0.590 | 0.000 | 0.619 | 0.835 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
| Serum C-reactive protein level before TCZ | |||||||||||
| Pearson correlation | 0.206 | 0.282 | 1 | .595∗ | .684∗ | 0.139 | −0.046 | −0.299 | −0.196 | −0.385 | 0.081 |
| Sig. (2-tailed) | 0.323 | 0.173 | 0.007 | 0.000 | 0.506 | 0.826 | 0.176 | 0.348 | 0.058 | 0.702 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
| d-dimer serum concentration | |||||||||||
| Pearson correlation | 0.085 | 0.165 | .595∗ | 1 | 0.140 | .771∗ | −.465† | −0.404 | −0.153 | −0.240 | −0.081 |
| Sig. (2-tailed) | 0.731 | 0.499 | 0.007 | 0.567 | 0.000 | 0.045 | 0.121 | 0.531 | 0.322 | 0.741 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
| Serum ferritin level | |||||||||||
| Pearson correlation | 0.097 | 0.148 | .684∗ | 0.140 | 1 | 0.038 | 0.211 | −0.195 | −0.221 | −0.181 | 0.004 |
| Sig. (2-tailed) | 0.652 | 0.491 | 0.000 | 0.567 | 0.861 | 0.323 | 0.398 | 0.299 | 0.396 | 0.984 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
| Neutrophil to lymphocyte ratio | |||||||||||
| Pearson correlation | 0.084 | 0.051 | 0.139 | .771∗ | 0.038 | 1 | −0.075 | −0.071 | −0.109 | −0.003 | −0.030 |
| Sig. (2-tailed) | 0.690 | 0.810 | 0.506 | 0.000 | 0.861 | 0.721 | 0.754 | 0.604 | 0.988 | 0.887 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
| Platelet count | |||||||||||
| Pearson correlation | 0.052 | −0.174 | −0.046 | −.465† | 0.211 | −0.075 | 1 | −0.139 | −0.117 | 0.361 | −0.293 |
| Sig. (2-tailed) | 0.806 | 0.405 | 0.826 | 0.045 | 0.323 | 0.721 | 0.537 | 0.579 | 0.076 | 0.154 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
| Serum IL-6 level after TCZ | |||||||||||
| Pearson correlation | −0.114 | −0.121 | −0.299 | −0.404 | −0.195 | −0.071 | −0.139 | 1 | .564∗ | 0.093 | .668∗ |
| Sig. (2-tailed) | 0.614 | 0.590 | 0.176 | 0.121 | 0.398 | 0.754 | 0.537 | 0.006 | 0.681 | 0.001 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
| Extubation | |||||||||||
| Pearson correlation | −.647∗ | −.657∗ | −0.196 | −0.153 | −0.221 | −0.109 | −0.117 | .564∗ | 1 | 0.091 | 0.377 |
| Sig. (2-tailed) | 0.000 | 0.000 | 0.348 | 0.531 | 0.299 | 0.604 | 0.579 | 0.006 | 0.666 | 0.063 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
| Serum IL-6 level before TCZ | |||||||||||
| Pearson correlation | −0.067 | −0.105 | −0.385 | −0.240 | −0.181 | −0.003 | 0.361 | 0.093 | 0.091 | 1 | −.663∗ |
| Sig. (2-tailed) | 0.749 | 0.619 | 0.058 | 0.322 | 0.396 | 0.988 | 0.076 | 0.681 | 0.666 | 0.000 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
| IL-6 Difference | |||||||||||
| Pearson correlation | −0.063 | −0.044 | 0.081 | −0.081 | 0.004 | −0.030 | −0.293 | .668∗ | 0.377 | −.663∗ | 1 |
| Sig. (2-tailed) | 0.764 | 0.835 | 0.702 | 0.741 | 0.984 | 0.887 | 0.154 | 0.001 | 0.063 | 0.000 | |
| N | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
TCZ = tocilizumab.
∗
Correlation is significant at the 0.01 level (2-tailed).
†
Correlation is significant at the 0.05 level (2-tailed).