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. 2021 May 7;16(5):e0251236. doi: 10.1371/journal.pone.0251236

Table 5. Diagnostic accuracy of lung ultrasound findings in adults.

Study LUS finding Patients PTB Sensitivity (95% CI) Specificity (95% CI)
Agostinis 2017 [34] Subpleural nodule 60 60 96.7 (88.5–99.6)
Lung consolidation 60 60 46.7 (33.7–60.0)
Pleural effusion 60 60 18.3 (9.5–30.4)
Miliary pattern 60 60 6.7 (1.9–16.2)
Cavitation 60 60 5.0 (1.0–13.9)
Babasa 2019* [35] Subpleural nodules or pleural effusion or consolidation or C-lines 131 ** 55.8 (45.7–65.5) 92.3 (75.7–99.1)
Fentress 2020 [33] Subpleural nodule 51 51 80.4 (66.9–90.2)
Lung consolidation 51 51 80.4 (66.9–90.2)
Pleural effusion 51 51 7.8 (2.2–18.9)
Miliary pattern 51 51 0.0 (0.0–7.0)
Cavitation 51 51 5.9 (1.2–16.2)
Montuori 2019 [9] Subpleural nodule 102 51 72.5 (58.3–84.1) 66.7 (52.1–79.2)
Lung consolidation 102 51 78.4 (64.7–88.7) 35.3 (22.4–49.9)
Pleural effusion 102 51 19.6 (9.8–33.1) 74.5 (60.4–85.7)
Miliary pattern
Cavitation 58 30 30.0 (14.7–49.4) 89.3 (71.7–97.7)
Wagih 2020 [36] Subpleural nodule 50 50 100.0 (92.9–100.0)
Lung consolidation
Pleural effusion 50 50 24.0 (13.1–38.2)
Miliary pattern 50 50 0.0 (0.0–7.1)
Cavitation 50 50 4.0 (0.4–13.7)

95% CI = exact binomial 95% confidence interval; LUS = lung ultrasound.

*raw numbers of true positives, false positive, false negatives and true negatives were unavailable; confidence intervals are as presented in abstract so may not correspond to other calculated confidence intervals.

**number of patients with PTB not reported.