Table 5. Diagnostic accuracy of lung ultrasound findings in adults.
Study | LUS finding | Patients | PTB | Sensitivity (95% CI) | Specificity (95% CI) |
---|---|---|---|---|---|
Agostinis 2017 [34] | Subpleural nodule | 60 | 60 | 96.7 (88.5–99.6) | |
Lung consolidation | 60 | 60 | 46.7 (33.7–60.0) | ||
Pleural effusion | 60 | 60 | 18.3 (9.5–30.4) | ||
Miliary pattern | 60 | 60 | 6.7 (1.9–16.2) | ||
Cavitation | 60 | 60 | 5.0 (1.0–13.9) | ||
Babasa 2019* [35] | Subpleural nodules or pleural effusion or consolidation or C-lines | 131 | ** | 55.8 (45.7–65.5) | 92.3 (75.7–99.1) |
Fentress 2020 [33] | Subpleural nodule | 51 | 51 | 80.4 (66.9–90.2) | |
Lung consolidation | 51 | 51 | 80.4 (66.9–90.2) | ||
Pleural effusion | 51 | 51 | 7.8 (2.2–18.9) | ||
Miliary pattern | 51 | 51 | 0.0 (0.0–7.0) | ||
Cavitation | 51 | 51 | 5.9 (1.2–16.2) | ||
Montuori 2019 [9] | Subpleural nodule | 102 | 51 | 72.5 (58.3–84.1) | 66.7 (52.1–79.2) |
Lung consolidation | 102 | 51 | 78.4 (64.7–88.7) | 35.3 (22.4–49.9) | |
Pleural effusion | 102 | 51 | 19.6 (9.8–33.1) | 74.5 (60.4–85.7) | |
Miliary pattern | |||||
Cavitation | 58 | 30 | 30.0 (14.7–49.4) | 89.3 (71.7–97.7) | |
Wagih 2020 [36] | Subpleural nodule | 50 | 50 | 100.0 (92.9–100.0) | |
Lung consolidation | |||||
Pleural effusion | 50 | 50 | 24.0 (13.1–38.2) | ||
Miliary pattern | 50 | 50 | 0.0 (0.0–7.1) | ||
Cavitation | 50 | 50 | 4.0 (0.4–13.7) |
95% CI = exact binomial 95% confidence interval; LUS = lung ultrasound.
*raw numbers of true positives, false positive, false negatives and true negatives were unavailable; confidence intervals are as presented in abstract so may not correspond to other calculated confidence intervals.
**number of patients with PTB not reported.