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. 2021 May 7;7(19):eabc1955. doi: 10.1126/sciadv.abc1955

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Fig. 1 — (A) Cutaway side view of the bacteriophage phi29 dsDNA packaging motor as determined by cryo-EM. Molecular envelopes of the connector, pRNA, and ATPase are shown in cyan, magenta, and blue, respectively. (B) Model of the mechanochemical cycle of the packaging motor as determined by single-molecule experiments [adapted from Chistol et al., 2012 (32)]. The top and bottom halves of the panel show the chemical and mechanical transitions in the dwell phase and burst phases, respectively. The presumed mechanochemical state of the motor trapped by ATP-γ-S is indicated by an asterisk.