Table 2.
Characteristics of patients with pneumonia
| Variable | COVID (-) [n = 12] | COVID (+) [n = 16] | P-value |
|---|---|---|---|
| Age (years) | 65 ± 24.9 | 60 ± 14.1 | 0.509 |
| Sex (Male; %) | 8 (66.7) | 11 (68.8) | 0.907 |
| BMI (Kg/sqm) | 23.8 ± 5.72 | 26.6 ± 5.24 | 0.211 |
|
Anamnesis COPD (%) Smoking habit (%) CAD (%) CHF (%) Hypertension (%) Diabetes (%) CKD (%) |
2 (16.7) 0 (0.0) 3 (25.0) 2 (16.7) 6 (50.0) 1 (8.3) 4 (33.3) |
3 (18.8) 3 (18.8) 4 (24.0) 1 (6.3) 7 (43.8) 4 (25.0) 4 (25.0) |
0.887 0.112 1.000 0.378 0.743 0.254 0.629 |
|
Arterial blood gas assay pCO2 (KPa) pO2 (KPa) Bicarbonate (mmol/L) Lactic acid (mmol/L) |
5.8 ± 1.79 10.8 ± 1.38 25.9 ± 3.95 1.5 [0.6; 1.8] |
4.6 ± 0.70 10.2 ± 5.58 23.7 ± 2.87 1.0 [0.7; 1.7] |
0.084 0.522 0.141 0.910 |
|
Biochemical parameters Haemoglobin (g/L) WBC (*10E9/L) Neutrophils (*10E9/L) Lymphocytes (*10E9/L) Monocytes (*10E9/L) Eosinophils (*10E9/L) Basophils (*10E9/L) C-reactive protein (mg/L) D-dimer (mg/L) PT-INR (a.u.) aPTT (sec) |
130 ± 20.6 9.5 ± 4.39 7.6 ± 4.49 0.9 ± 0.61 0.58 ± 0.213 0.05 ± 0.050 0.03 ± 0.024 17 [9; 105] 1.02 [0.64; 3.22] 1.3 [1.1; 1.5] 31 [27; 37] |
137 ± 17.5 5.7 ± 2.12 4.1 ± 1.86 0.9 ± 0.36 0.33 ± 0.174 0.05 ± 0.132 0.03 ± 0.028 49 [14; 122] 1.09 [0.63; 3.61] 1.1 [1.0; 1.2] 33 [30; 36] |
0.305 0.018 0.030 0.730 0.003 0.984 0.596 0.312 0.906 0.084 0.455 |
|
Outcome Hospitalization (days) Orotracheal intubation (%) Death (%) |
8 [4; 16] 4 (33.3) 0 (0.0) |
14 [8; 19] 9 (56.3) 2 (12.5) |
0.119 0.229 0.204 |
Characteristic of patients with diagnosis of pneumonia (n = 28), with or without infection by SARS-CoV-2. Normally distributed variables (age, BMI, pCO2, pO2, bicarbonate, haemoglobin, WBC) are expressed as mean ± standard deviation and were analyzed by T-student test for independent samples; non normally distributed variables (lactic acid, C-reactive protein, D-dimer, PT-INR, aPTT, hospitalization) are expressed as median [interquartile range] and analyzed by Mann-Whitney test; categorical variables (sex, anamnesis, orotracheal intubation, death) are expressed as absolute number (percentage) and analyzed by Chi square test (or Fisher test, when appropriated); a P < 0.05 was considered significant and shown in bold. COPD, Chronic Obstructive Pulmonary Disease; CAD, Coronary Artery Disease; CHF, Chronic Heart Failure (defined as ejection fraction < 35%); CKD, Chronic Kidney Disease (defined as eGFR < 60 mL/min); WBC, White Blood Cells.