Table 1.
MC production from hESCs.
| Type | MCs generated from one hESC |
Reference | |
|---|---|---|---|
| c-kit+Tryptase+ | Tryptase+Chymase+ | ||
| Coculture D8 CD34+c-kit+a | 258.35 ± 32.65 (100%) | 258.35 ± 32.65 (100%) | This study |
| Coculture D14 CD34+CD45+b | 163.33 ± 10.36 (100%) | 157.94 ± 3.27 (96.7% ± 2%) | |
| CB CD34+c | 595.28 ± 95.62 (100%) | 111.32 ± 5.96 (18.7% ± 1%) | |
| Coculture D12 CD34+d | NA | 1.5 ± 0.3 (>90%) | Kovarova et al. (2010) |
| Embryoid body (EB) e | NA | 9.7 ± 4.7 (>90%) | |
a
MCs generated from hESC/AGM-S3 coculture D8 CD34+c-kit+ cells after 12 weeks.
b
MCs generated from hESC/AGM-S3 coculture D14 CD34+CD45+ cells after 12 weeks.
c
MCs generated from CB CD34+ cells after 12 weeks.
d
MCs generated from hESC/OP9 coculture D12 CD34+ cells after 12 weeks.
e
MCs generated from hESC-derived EB cells after 12 weeks.