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. 2021 Mar 15;11(5):jkab079. doi: 10.1093/g3journal/jkab079

Figure 3.

Figure 3

Comparison of pericardial fat and tongue fat volumes. The distribution of (A) pericardial fat and (B) tongue fat are shown across the eight founder strains. Vertical error bars represent the observed mean ± standard deviation. The NZO/HILtJ and C57BL/6J strains had significantly more pericardial fat than all other strains. We observed a significant heritability estimate of 0.621 (95% CI: 0.503, 0.740) for pericardial fat. This estimate remained significant after controlling for body weight (0.439 [0.287, 0.590]). For tongue fat, the NZO/HILtJ again demonstrated significantly more fat than other strains, but the PWK/PhJ strain, rather than C57BL/6J, also demonstrated significantly higher volume than all strains except NZO/HILtJ. Tongue fat volume had high heritability (0.765 [0.658, 0.872]), which remained significant when controlling for body weight (0.577 [0.385, 0.769]). Thus, both pericardial fat and tongue fat show significant heritability adjusting for body weight.