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. 2021 May 3;8:333–348. doi: 10.2147/JHC.S306484

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© 2021 Zhang et al.

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CCDC144NL-AS1 promotes WDR5 to be recruited to the promoter region of MMPs and CDKs. ChIP assay showed that (A) the recruitment of WDR5 and (B) the H3K4me3 level in the promoter region of MMP2, MMP9, CDK1, CDK2, and CDK4 was regulated by CCDC144NL-AS1/miR-940 axis. Data were expressed as mean ± SEM. *P<0.05, **P<0.001.