Wang 2019.

Study name	A study of the impact of home‐based cardiac rehabilitation on outcomes after transcatheter aortic valve replacement (TAVR)
Methods	Parallel‐assignment RCT
Participants	Adult Chinese patients after transcatheter aortic valve replacement (TAVR)
Interventions	Placebo comparator; control group: routine care; experimental group/interventional group: home‐based cardiac rehabilitation
Outcomes	Primary outcomes 6‐minute walk test [Time Frame: 6 weeks, total distance walked in meters during 6 minutes] Secondary outcomes Number of participants who will die [Time Frame: 6 weeks, 12 months, number of participants who die during the study due to cardiovascular or non‐cardiovascular causes] Number of participants re‐hospitalised [Time Frame: 6 weeks, 12 months, number of participants re‐hospitalised during the study] Number of participants completing home‐based cardiac rehabilitation [Time Frame: 6 weeks, number of participants completing home‐based cardiac rehabilitation] Cardiac function [Time Frame: 12 months, ejection fraction estimated by echocardiography] Aortic valve function [Time Frame: 12 months, aortic valve function estimated by echocardiography] Number of participants injured [Time Frame: 6 weeks, number of participants injured or who die during the course of home‐based cardiac rehabilitation] Time spent performing activities [Time Frame: 6 weeks, 12 months, number of minutes in a typical week that participants spent performing activities] 6‐minute walk test [Time Frame: 12 months, total distance walked in meters during 6 minutes]
Starting date	1 January 2020
Contact information	wxyonce@zju.edu.cn
Notes	Estimated enrolment: 300 participants. Estimated study finish date: 31 December 2023 Location: Second Affiliated Hospital, School of Medicine, Zhejiang University

AVR: aortic valve replacement.
CABG: coronary artery bypass graft.
ECG: electrocardiogram.
KCCQ: Kansas City Cardiomyopathy Questionnaire.
LOS: length of stay.
MACE: major adverse cardiovascular event.
MVR: mitral valve replacement.
NYHA: New York Heart Association.
PVO₂: mixed venous oxygen tension.
RCT: randomised controlled trial.
TAVR: transaortic valve replacement.
VO₂: maximal oxygen consumption.