Table 5.

Major adverse cerebral and cardiovascular events (MACCE) risk factors analysis in very long-term observation.

	MACCE	Death	MI	RE-PCI	Stroke/TIA
Male sex	1.17 (0.62–2.16)	0 (0–1.13)	1.35 (0.37–4.55)	1.42 (0.68–2.91)	3.33 (0.58–17.81)
	p = 0.72	p = 0.15	p = 0.83	p = 0.41	p = 0.24
Age > 57 years	1.72 (1.03–2.86)	2.29 (0.88–6.83)	0.92 (0.32–2.62)	1.47 (0.79–2.73)	6.30 (0.75–139)
	p = 0.02	p = 0.08	p = 0.94	p = 0.25	p = 0.05
EF < 50%	3.03 (1.49–6.25)	3.55 (1.03–11.59	3.56 (1.49–20.6)	0.49 (0.19–1.31)	3.76 (0.47–24.55)
	p = 0.001	p = 0.03	p = 0.005	p = 0.18	p = 0.10
Diabetes	1.45 (0.72–2.88)	1.98 (0.53–6.72)	1.49 (0.33–5.70)	1.32 (0.55–3.07)	1.0 (0.98–1.03)
	p = 0.34	p = 0.40	p = 0.79	p = 0.64	p = 0.69
Arterial hypertension	1.05 (0.63–1.77)	1.02 (0.36–2.95)	1.31 (0.45–3.86)	0.79 (0.42–1.48)	4.60 (0.52–104)
	p = 0.95	p = 0.84	p = 0.76	p = 0.52	p = 0.12
Incomplete	3.30 (0.44–19.64)	0 (0–32.03)	6.58 (1–109.1)	2.18 (0.80–3.47)	0 (0–107.67)
revascularization	p = 0.37	p = 0.44	p = 0.05	p = 0.46	p = 0.79
PCI in history	2.13 (1.28–3.54)	2.15 (0.79–5.82)	2.70 (0.94–7.80)	2.11 (1.14–3.91)	1.76 (0.31–9.38)
	p = 0.002	p = 0.09	p = 0.06	p = 0.01	p = 0.73
MI in history	0.89 (0.52–1.53)	1.12 (0.38–3.25)	1.83 (0.64–5.28)	0.73 (0.37–1.44)	0.32 (0.01–2.79)
	p = 0.76	p = 0.98	p = 0.32	p = 0.42	p = 0.49
CCS class 3–4 vs. 1–2	1.02 (0.34–2.83)	1.0 (0.95–1.05)	1.0 (0.95–1.05)	0.92 (0.22–3.28)	0 (0–13.14)
	p = 0.97	p = 0.87	p = 0.87	p = 0.86	p = 0.88
NYHA class II vs. I	2.63 (1.15–5.93)	3.12 (0.88–12.33)	3.12 (0.88–12.33)	1.32 (0.38–4.12)	0 (0–13.38)
	p = 0.01	p = 0.08	p = 0.08	p = 0.83	p = 0.87
Urgent surgery	0.47 (0.11–1.60)	1.45 (0–6.82)	0.99 (0.96–1.03)	0 (0–2.13)	0 (0–9.78)
	p = 0.28	p = 0.95	p = 0.84	p = 0.27	p = 0.96

CCS — Canadian Cardiovascular Society; EF — ejection fraction; MI — myocardial infarction; NYHA — New York Heart Association; PCI — percutaneous coronary intervention; TIA — transient ischemic attack